The rearrangement of eight new Z-arylhydrazones of 3-benzoyl-5-phenylisoxazoles (3d–k) into the relevant 2-aryl-4-phenacyl-2H-1,2,3-triazoles (4d–k) in dioxane/water solution at different proton concentrations has been quantitatively studied in a wide temperature range (293–333 K). The data collected together with some our previous ones on compounds 3a–c have allowed a deep study of the substituent effects on the course of the rearrangement, thus increasing our knowledge on the Boulton–Katritzky reactions in isoxazole derivatives and on the temperature effects on free energy relationships
Frenna, V., Palumbo Piccionello, A., Spinelli, D., Ghelfi, F. (2015). On the rearrangement of some Z-arylhydrazones of 3-benzoyl-5-phenylisoxazoles into 2-aryl-4-phenacyl-2H-1,2,3-triazoles: a kinetic study of the substituent effects in Boulton-Katritzky reactions. TETRAHEDRON, 71(39), 7315-7322 [10.1016/j.tet.2015.04.007].
On the rearrangement of some Z-arylhydrazones of 3-benzoyl-5-phenylisoxazoles into 2-aryl-4-phenacyl-2H-1,2,3-triazoles: a kinetic study of the substituent effects in Boulton-Katritzky reactions
FRENNA, Vincenzo;PALUMBO PICCIONELLO, Antonio;
2015-01-01
Abstract
The rearrangement of eight new Z-arylhydrazones of 3-benzoyl-5-phenylisoxazoles (3d–k) into the relevant 2-aryl-4-phenacyl-2H-1,2,3-triazoles (4d–k) in dioxane/water solution at different proton concentrations has been quantitatively studied in a wide temperature range (293–333 K). The data collected together with some our previous ones on compounds 3a–c have allowed a deep study of the substituent effects on the course of the rearrangement, thus increasing our knowledge on the Boulton–Katritzky reactions in isoxazole derivatives and on the temperature effects on free energy relationshipsFile | Dimensione | Formato | |
---|---|---|---|
Tetrahedron 2015.pdf
Solo gestori archvio
Descrizione: Articolo Principale
Dimensione
486.93 kB
Formato
Adobe PDF
|
486.93 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.