The diagnosis of IgE-mediated egg allergy lies both on a compatible clinical history and on the results of skin prick tests (SPTs) and IgEs levels. Both tests have good sensitivity but low specificity. For this reason, oral food challenge (OFC) is the ultimate gold standard for the diagnosis. The aim of the present paper is to systematically review the literature in order to identify, analyze and synthesize the predictive value of SPT and specific IgEs both to egg white and main egg allergens and to review the cut-offs suggested in the literature.
Calvani, M., Arasi, S., Bianchi, A., Caimmi, D., Cuomo, B., Dondi, A., et al. (2015). Is it possible to make a diagnosis of raw, heated and baked egg allergy in children using cut-offs? A systematic review. PEDIATRIC ALLERGY AND IMMUNOLOGY(6), 509-521 [10.1111/pai.12432].
Is it possible to make a diagnosis of raw, heated and baked egg allergy in children using cut-offs? A systematic review
LA GRUTTA, Stefania;
2015-01-01
Abstract
The diagnosis of IgE-mediated egg allergy lies both on a compatible clinical history and on the results of skin prick tests (SPTs) and IgEs levels. Both tests have good sensitivity but low specificity. For this reason, oral food challenge (OFC) is the ultimate gold standard for the diagnosis. The aim of the present paper is to systematically review the literature in order to identify, analyze and synthesize the predictive value of SPT and specific IgEs both to egg white and main egg allergens and to review the cut-offs suggested in the literature.
| File | Dimensione | Formato | |
|---|---|---|---|
|
Calvani_2015-PAI _Is it possible to make a diagnosis of raw, heated and baked egg allergy in children using cut-offs.pdf
accesso aperto
Descrizione: Post print
Dimensione
313.73 kB
Formato
Adobe PDF
|
313.73 kB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
