Rapid titration with intravenous morphine (IV-MO) provides fast and efficient pain relief in cancer patients with severe-excruciating pain. However, some patients, after an initially favourable response, can develop an hyperexcitated state unrelieved or worsened by further dose increments.
Mercadante, S., Ferrera, P., Arcuri, E., Casuccio, A. (2012). Opioid-induced hyperalgesia after rapid titration with intravenous morphine: Switching and re-titration to intravenous methadone. ANNALS OF PALLIATIVE MEDICINE, 1(1), 10-13 [10.3978/j.issn.2224-5820.2012.01.02].
Opioid-induced hyperalgesia after rapid titration with intravenous morphine: Switching and re-titration to intravenous methadone
CASUCCIO, Alessandra
2012-01-01
Abstract
Rapid titration with intravenous morphine (IV-MO) provides fast and efficient pain relief in cancer patients with severe-excruciating pain. However, some patients, after an initially favourable response, can develop an hyperexcitated state unrelieved or worsened by further dose increments.
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