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EnglishWe evaluated the relationship between motor and neuropsychological deficits in subjects affected by amnestic Mild Cognitive Impairment (aMCI) and {early} Alzheimer's Disease (AD). Kinematics of goal-directed movement of aMCI and AD subjects were compared to those of age-matched control subjects. AD showed a slowing down of motor performance compared to aMCI and controls. No relationships were found between motor and cognitive performances in both AD and aMCI. Our results suggest that the different motor behaviour between AD and aMCI cannot be related to memory deficits, probably reflecting the initial degeneration of parietal-frontal circuits for movement planning. The onset of motor dysfunction in early AD could represent the transition from aMCI to AD.
Camarda, R., Camarda, C., Monastero, R., Grimaldi, S., Camarda, L., Pipia, C., et al. (2007). Movements execution in amnestic mild cognitive impairment and Alzheimer's disease. BEHAVIOURAL NEUROLOGY, 18(18), 135-142 [10.1155/2007/845914].
| Data di pubblicazione: | 2007 | |
| Titolo: | Movements execution in amnestic mild cognitive impairment and Alzheimer's disease. | |
| Autori: | ||
| Citazione: | Camarda, R., Camarda, C., Monastero, R., Grimaldi, S., Camarda, L., Pipia, C., et al. (2007). Movements execution in amnestic mild cognitive impairment and Alzheimer's disease. BEHAVIOURAL NEUROLOGY, 18(18), 135-142 [10.1155/2007/845914]. | |
| Rivista: | ||
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1155/2007/845914 | |
| Abstract: | We evaluated the relationship between motor and neuropsychological deficits in subjects affected by amnestic Mild Cognitive Impairment (aMCI) and {early} Alzheimer's Disease (AD). Kinematics of goal-directed movement of aMCI and AD subjects were compared to those of age-matched control subjects. AD showed a slowing down of motor performance compared to aMCI and controls. No relationships were found between motor and cognitive performances in both AD and aMCI. Our results suggest that the different motor behaviour between AD and aMCI cannot be related to memory deficits, probably reflecting the initial degeneration of parietal-frontal circuits for movement planning. The onset of motor dysfunction in early AD could represent the transition from aMCI to AD. | |
| Settore Scientifico Disciplinare: | Settore MED/26 - Neurologia | |
| Appare nelle tipologie: | 1.01 Articolo in rivista |
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| BN-2007-18-3-845914.pdf | N/A | Open Access Visualizza/Apri |
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