The antiproliferative activity of fresh fruit juices extracted from Citrus sinensis (cv. Washington Navel and cv. Sanguinello), C. deliciosa cv. Avana, C. clementina cv. Nules, C. aurantium subspp. myrtifolia, was evaluated against K562 (human chronic myelogenous leukemia), HL-60 (human leukemia) and MCF-7 (human breast adenocarcinoma) cell lines. All the juices tested showed antiproliferative activity. Moreover, the pattern of the main flavanone compounds in the juices has been determined by HPLC analysis.
CAMARDA, L., DI STEFANO, V., FATTA DAL BOSCO, S., SCHILLACI, D. (2007). ANTIPROLIFERATIVE ACTIVITY OF CITRUS JUICES AND HPLC EVALUATION OF THEIR FLAVONOID COMPOSITION. FITOTERAPIA, 78(6), 426-429 [10.1016/j.fitote.2007.02.020].
ANTIPROLIFERATIVE ACTIVITY OF CITRUS JUICES AND HPLC EVALUATION OF THEIR FLAVONOID COMPOSITION
CAMARDA, Lorenzo;DI STEFANO, Vita;SCHILLACI, Domenico
2007-01-01
Abstract
The antiproliferative activity of fresh fruit juices extracted from Citrus sinensis (cv. Washington Navel and cv. Sanguinello), C. deliciosa cv. Avana, C. clementina cv. Nules, C. aurantium subspp. myrtifolia, was evaluated against K562 (human chronic myelogenous leukemia), HL-60 (human leukemia) and MCF-7 (human breast adenocarcinoma) cell lines. All the juices tested showed antiproliferative activity. Moreover, the pattern of the main flavanone compounds in the juices has been determined by HPLC analysis.
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