Several 1,3-thiazolidin-4-ones bearing a 2,6-dihalophenyl group at C-2 and a variously substituted phenyl ring at N-3 have been synthesized and tested as anti-HIV agents. The results of the in vitro tests showed that some of them proved to be effective inhibitors of HIV-1 replication.

Rao, A., Carbone, A., Chimirri, A., De Clercq, E., Monforte, A., Monforte, P., et al. (2002). Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-ones. IL FARMACO, 58(58), 115-120.

Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-ones.

CARBONE, Anna;
2002

Abstract

Several 1,3-thiazolidin-4-ones bearing a 2,6-dihalophenyl group at C-2 and a variously substituted phenyl ring at N-3 have been synthesized and tested as anti-HIV agents. The results of the in vitro tests showed that some of them proved to be effective inhibitors of HIV-1 replication.
Rao, A., Carbone, A., Chimirri, A., De Clercq, E., Monforte, A., Monforte, P., et al. (2002). Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-ones. IL FARMACO, 58(58), 115-120.
File in questo prodotto:
File Dimensione Formato  
Farmaco2003-58,115.pdf

non disponibili

Dimensione 131.02 kB
Formato Adobe PDF
131.02 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10447/107675
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 66
  • ???jsp.display-item.citation.isi??? ND
social impact