Background. Giant Condyloma Acuminatum (GCA) is a rare, slow growing, large cauliflower tumor of the penile foreskin and peria- nal region with benign histologic appearance but high propensity for lo- cal invasion and recurrences. GCA is associated with Human Papillo- ma Virus (HPV) types 6 and 11 and it also has considerable risk of neo- plastic transformation into fully invasive squamous cell carcinoma in- to about 5 years. Objective. Because of the rarity of perianal GCA, to date there is no general agreement on the best method for treatment. We wanted to know if surgical approach only was a good method to treat our case. Case report. A 28 years old man, HIV-negative, with a 4 years hi- story of perianal GCA quickly growing underwent full tickness local excision at least 0,7 cm margin of normal tissue with skin grafting taken from the thighs. Fecal contamination was avoided by diet and lo- peramide per os. At two years follow-up no recurrence was detected. Conclusion. Surgical approach with full tickness excision and im- mediate skin-grafting and regular follow-up demonstrated effective to treat GCA and to minimize disease recurrence.

Patti, R., Aiello, P., Angelo, G.L., & Di Vita, G. (2012). Giant condyloma acuminatum quickly growing: case report. IL GIORNALE DI CHIRURGIA, 33(10), 327-330.

Giant condyloma acuminatum quickly growing: case report

DI VITA, Gaetano Giuseppe
2012

Abstract

Background. Giant Condyloma Acuminatum (GCA) is a rare, slow growing, large cauliflower tumor of the penile foreskin and peria- nal region with benign histologic appearance but high propensity for lo- cal invasion and recurrences. GCA is associated with Human Papillo- ma Virus (HPV) types 6 and 11 and it also has considerable risk of neo- plastic transformation into fully invasive squamous cell carcinoma in- to about 5 years. Objective. Because of the rarity of perianal GCA, to date there is no general agreement on the best method for treatment. We wanted to know if surgical approach only was a good method to treat our case. Case report. A 28 years old man, HIV-negative, with a 4 years hi- story of perianal GCA quickly growing underwent full tickness local excision at least 0,7 cm margin of normal tissue with skin grafting taken from the thighs. Fecal contamination was avoided by diet and lo- peramide per os. At two years follow-up no recurrence was detected. Conclusion. Surgical approach with full tickness excision and im- mediate skin-grafting and regular follow-up demonstrated effective to treat GCA and to minimize disease recurrence.
Settore MED/18 - Chirurgia Generale
Patti, R., Aiello, P., Angelo, G.L., & Di Vita, G. (2012). Giant condyloma acuminatum quickly growing: case report. IL GIORNALE DI CHIRURGIA, 33(10), 327-330.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10447/104478
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