| Nome |
# |
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Therapeutic strategies to counteract antibiotic resistance in MRSA biofilm-associated infections, file e3ad8925-3833-da0e-e053-3705fe0a2b96
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559
|
|
Nanostructured Lipid Carriers-Containing Anticancer Compounds: Preparation, Characterization, and Cytotoxicity Studies, file e3ad891d-c3a4-da0e-e053-3705fe0a2b96
|
224
|
|
A multivariate analysis on non-nucleoside HIV-1 reverse transcriptase inhibitors and resistance induced by mutation, file e3ad8917-11aa-da0e-e053-3705fe0a2b96
|
215
|
|
Synthesis and antitumor activity of new thiazole nortopsentin analogs, file e3ad891a-83a9-da0e-e053-3705fe0a2b96
|
203
|
|
Inhibitors of antibiotic resistance mechanisms: clinical applications and future perspectives, file e3ad8921-f6a7-da0e-e053-3705fe0a2b96
|
200
|
|
Docking of indolo- and pyrrolo-pyrimidines to DNA. New DNA-interactive polycycles from amino-indoles/pyrroles and BMMA., file e3ad891e-8b4a-da0e-e053-3705fe0a2b96
|
169
|
|
An overview of recent molecular dynamics applications as medicinal chemistry tools for the undruggable site challenge, file e3ad891d-4c46-da0e-e053-3705fe0a2b96
|
164
|
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3-(6-Phenylimidazo [2,1-b][1,3,4]thiadiazol-2-yl)-1HIndole derivatives as new anticancer agents in the treatment of pancreatic ductal adenocarcinoma, file e3ad8921-b7d1-da0e-e053-3705fe0a2b96
|
158
|
|
3-[4-(1H-indol-3-yl)-1,3-thiazol-2-yl]-1H-pyrrolo[2,3-b]pyridines, nortopsentin Analogues with antiproliferative activity, file e3ad8918-0e4b-da0e-e053-3705fe0a2b96
|
121
|
|
Synthesis and antiproliferative activity of thiazolyl-bis-pyrrolo[2,3-b]pyridines and indolyl-thiazolyl-pyrrolo[2,3-c]pyridines, nortopsentin analogues, file e3ad8917-2f50-da0e-e053-3705fe0a2b96
|
120
|
|
CHK1 inhibitor sensitizes resistant colorectal cancer stem cells to nortopsentin, file e3ad8926-ec13-da0e-e053-3705fe0a2b96
|
118
|
|
New Tripentone Analogs with Antiproliferative Activity, file e3ad891c-c034-da0e-e053-3705fe0a2b96
|
115
|
|
Interleukin 3- receptor targeted exosomes inhibit in vitro and in vivo chronic myelogenous Leukemia cell growth, file e3ad891a-baa2-da0e-e053-3705fe0a2b96
|
114
|
|
New 1,2,4-Oxadiazole Nortopsentin Derivatives with Cytotoxic Activity, file e3ad891e-a585-da0e-e053-3705fe0a2b96
|
111
|
|
New Thiazole Nortopsentin Analogues Inhibit Bacterial Biofilm Formation, file e3ad891f-0759-da0e-e053-3705fe0a2b96
|
103
|
|
In vitro digestion of beta glucan enriched pasta: polysaccharide molecular characterization and antioxidant activity of bioaccessible fraction., file e3ad8917-364f-da0e-e053-3705fe0a2b96
|
100
|
|
Bacterial Biofilm Inhibition in the Development of Effective Anti-Virulence Strategy, file e3ad891e-f1f2-da0e-e053-3705fe0a2b96
|
96
|
|
Itraconazole inhibits nuclear delivery of extracellular vesicle cargo by disrupting the entry of late endosomes into the nucleoplasmic reticulum, file e3ad8927-161b-da0e-e053-3705fe0a2b96
|
89
|
|
Thiazole Analogues of the Marine Alkaloid Nortopsentin as Inhibitors of Bacterial Biofilm Formation, file e3ad8925-1cf2-da0e-e053-3705fe0a2b96
|
73
|
|
In vitro digestion of beta glucan enriched pasta and antioxidant potential of digesta, file e3ad8916-cd37-da0e-e053-3705fe0a2b96
|
43
|
|
Synthesis and Antiproliferative Activity of [1,2,4]triazino[4,3-a]indoles, file e3ad891e-64ff-da0e-e053-3705fe0a2b96
|
35
|
|
Water-soluble isoindolo[2,1-a]quinoxalin-6-imines: In vitro antiproliferative activity and molecular mechanism(s) of action, file e3ad8928-0b41-da0e-e053-3705fe0a2b96
|
28
|
|
Pyrazolo[3,4-h]quinolines promising photosensitizing agents in the treatment of cancer, file e3ad8927-ee1f-da0e-e053-3705fe0a2b96
|
21
|
|
Quality characteristics and in vitro digestibility study of barley flour enriched ditalini pasta, file e3ad8928-42af-da0e-e053-3705fe0a2b96
|
19
|
|
Pyrazolo[3,4-h]quinolines promising photosensitizing agents in the treatment of cancer, file e3ad8918-1460-da0e-e053-3705fe0a2b96
|
15
|
|
Synthesis and biological evaluation of pyrrolo[3’,2’:6,7]cyclohepta[1,2-d]pyrimidin-2-amines, file e3ad8916-c915-da0e-e053-3705fe0a2b96
|
14
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|
New topoisomerase I inhibitors with condensed-azaindole structure, file e3ad8916-60d7-da0e-e053-3705fe0a2b96
|
13
|
|
Quality, functional and sensory evaluation of pasta fortified with extracts from Opuntia ficus-indica cladodes, file e3ad8928-1468-da0e-e053-3705fe0a2b96
|
12
|
|
Structural Manipulations of Marine Natural Products Inspire a New Library of 3-Amino-1,2,4-Triazine PDK Inhibitors Endowed with Antitumor Activity in Pancreatic Ductal Adenocarcinoma, file a835ba4a-94cf-4912-85bc-99eaf1072438
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11
|
|
Pyrazolo[3,4-h]quinolin-2-ones with photobiological properties, file e3ad8916-5209-da0e-e053-3705fe0a2b96
|
10
|
|
Antitumor activity of 2,5-bis-(3’-indolyl)-pyrroles, deaza-analogues of Nortopsentins, file e3ad8916-60d2-da0e-e053-3705fe0a2b96
|
10
|
|
Quality characteristics and in vitro digestibility study of barley flour enriched ditalini pasta, file e3ad8919-1f95-da0e-e053-3705fe0a2b96
|
9
|
|
Synthesis and antiproliferative mechanism of action of pyrrolo[3′,2′:6,7] cyclohepta[1,2-d]pyrimidin-2-amines as singlet oxygen photosensitizers, file e3ad8919-6354-da0e-e053-3705fe0a2b96
|
9
|
|
Synthesis and antiproliferative mechanism of action of pyrrolo[3′,2′:6,7] cyclohepta[1,2-d]pyrimidin-2-amines as singlet oxygen photosensitizers, file e3ad8928-3f0c-da0e-e053-3705fe0a2b96
|
9
|
|
Quality, functional and sensory evaluation of pasta fortified with extracts from Opuntia ficus-indica cladodes, file e3ad8922-09b5-da0e-e053-3705fe0a2b96
|
8
|
|
HIV-1-induced nuclear invaginations mediated by VAP-A, ORP3, and Rab7 complex explain infection of activated T cells, file 15fabc85-bf03-4a11-b3f0-5b23d8510b26
|
7
|
|
Biological evaluation of new 1,2,4-oxadiazole topsentin analogs as anticancer agents, file e3ad891e-a3a2-da0e-e053-3705fe0a2b96
|
7
|
|
2-substituted-[1,3]thiazolo[4,5-e]isoindoles as kinases inhibiting compounds, file e3ad8916-7884-da0e-e053-3705fe0a2b96
|
6
|
|
4,5,6,9-TETRAHYDROPYRROLO[2',3'-3,4]CYCLOEPTA[1,2-d]ISOSSAZOLE, PROCESS FOR THEIR PRODUCTION AND THEIR USES AS ANTITUMOR AGENTS, file e3ad891a-9757-da0e-e053-3705fe0a2b96
|
6
|
|
An overview on the recent developments of 1,2,4-triazine derivatives as anticancer compounds, file e3ad891b-e791-da0e-e053-3705fe0a2b96
|
6
|
|
Biological Evaluation of the Antiproliferative and Anti-migratory Activity of a Series of 3-(6-Phenylimidazo[2,1-b][1,3,4]thiadiazol-2-yl)-1H-indole Derivatives against Pancreatic Cancer Cells*, file e3ad8920-d2f4-da0e-e053-3705fe0a2b96
|
6
|
|
New Imidazo[2,1-b][1,3,4]Thiadiazole Derivatives Inhibit FAK Phosphorylation and Potentiate the Antiproliferative Effects of Gemcitabine Through Modulation of the Human Equilibrative Nucleoside Transporter-1 in Peritoneal Mesothelioma, file e3ad8923-ce14-da0e-e053-3705fe0a2b96
|
6
|
|
1,2,4-Oxadiazole Topsentin Analogs with Antiproliferative Activity against Pancreatic Cancer Cells, Targeting GSK3β Kinase, file e3ad8925-14cb-da0e-e053-3705fe0a2b96
|
6
|
|
1,2,4-Amino-triazine derivatives as pyruvate dehydrogenase kinase inhibitors: Synthesis and pharmacological evaluation, file 0f7b513c-f3d7-4bd6-b58e-a866350cb766
|
5
|
|
Synthesis, antitumor activity and CDK1 inhibiton of new thiazole nortopsentin analogues, file e3ad891b-405c-da0e-e053-3705fe0a2b96
|
5
|
|
A Multivariate Analysis of HIV-1 Protease Inhibitors and Resistance Induced by Mutation, file e3ad891d-cf6d-da0e-e053-3705fe0a2b96
|
5
|
|
Synthetic small molecules as anti-biofilm agents in the struggle against antibiotic resistance, file e3ad891e-a37a-da0e-e053-3705fe0a2b96
|
5
|
|
Metabolomics-assisted discovery of a new anticancer GLS-1 inhibitor chemotype from a nortopsentin-inspired library: From phenotype screening to target identification, file e3ad8928-3102-da0e-e053-3705fe0a2b96
|
5
|
|
Discovery of the 3-Amino-1,2,4-triazine-Based Library as Selective PDK1 Inhibitors with Therapeutic Potential in Highly Aggressive Pancreatic Ductal Adenocarcinoma, file 31ecfe93-cdae-4780-b102-f4bf81a1c1b8
|
4
|
|
Water-soluble isoindolo[2,1-a]quinoxalin-6-imines: In vitro antiproliferative activity and molecular mechanism(s) of action, file e3ad8918-1468-da0e-e053-3705fe0a2b96
|
4
|
|
The potential of neurotrophic tyrosine kinase (NTRK) inhibitors for treating lung cancer, file e3ad8919-0184-da0e-e053-3705fe0a2b96
|
4
|
|
Preclinical Activity of New [1,2]Oxazolo[5,4-e]isoindole Derivatives in Diffuse Malignant Peritoneal Mesothelioma, file e3ad8919-a24e-da0e-e053-3705fe0a2b96
|
4
|
|
New Topsentin analogs as inhibitors of biofilm formation, file e3ad891e-fc69-da0e-e053-3705fe0a2b96
|
4
|
|
Synthesis and antitumor activity of new thiazole nortopsentin analogs, file e3ad8921-e257-da0e-e053-3705fe0a2b96
|
4
|
|
Eight-Membered Rings With Two Heteroatoms 1,3, file 3c0e1d49-2e3f-48f2-aa63-a39c84ad2e6e
|
3
|
|
Synthesis of isoindolo[1,4]benzoxazinone and isoindolo[1,5]benzoxazepine: two new ring systems of pharmaceutical interest, file e3ad8918-1464-da0e-e053-3705fe0a2b96
|
3
|
|
Aza-isoindolo and isoindolo-azaquinoxaline derivatives with antiproliferative activity, file e3ad8918-146f-da0e-e053-3705fe0a2b96
|
3
|
|
Quality characteristic and in vitro digestibility study of barley flour enriched ditalini pasta, file e3ad8918-1c9d-da0e-e053-3705fe0a2b96
|
3
|
|
4,5,6,9-tetraidropirrolo[2',3':3,4] cicloepta[1,2-d] isossazoli, procedimento per la loro produzione e loro uso come antitumorali, file e3ad891a-8ae1-da0e-e053-3705fe0a2b96
|
3
|
|
Pharmaceutical Approaches to Target Antibiotic Resistance Mechanisms, file e3ad891b-6f56-da0e-e053-3705fe0a2b96
|
3
|
|
1,3,5-Triazines: A promising scaffold for anticancer drugs development, file e3ad891b-d49f-da0e-e053-3705fe0a2b96
|
3
|
|
Synthesis and antitumor activities of 1,2,3-triazines and their benzo- and heterofused derivatives, file e3ad891b-e322-da0e-e053-3705fe0a2b96
|
3
|
|
2,6-Disubstituted imidazo[2,1-b][1,3,4]thiadiazole derivatives as potent staphylococcal biofilm inhibitors, file e3ad891e-d678-da0e-e053-3705fe0a2b96
|
3
|
|
Synthesis of novel 1,2,4-oxadiazole topsentin analogs with antitumor activity, file e3ad891e-fc1e-da0e-e053-3705fe0a2b96
|
3
|
|
Eight-membered heterocycles with two heteroatoms in a 1,5-relationship of interest in medicinal chemistry, file e3ad8921-b7d5-da0e-e053-3705fe0a2b96
|
3
|
|
Thiazoles, Their Benzofused Systems, and Thiazolidinone Derivatives: Versatile and Promising Tools to Combat Antibiotic Resistance, file e3ad8923-c04a-da0e-e053-3705fe0a2b96
|
3
|
|
1,2,4-Oxadiazole topsentin analogs as staphylococcal biofilm inhibitors targeting the bacterial transpeptidase sortase A, file e3ad8925-4d33-da0e-e053-3705fe0a2b96
|
3
|
|
PYRROLO[3,4-H]QUINAZOLINES WITH ANTITUMOR ACTIVITY, file e3ad8915-c9a3-da0e-e053-3705fe0a2b96
|
2
|
|
SYNTHESIS AND ANTITUMOR ACTIVITY OF 3-[2-PHENYL-1,3-THIAZOL-4-YL]-1H-7-AZAINDOLES, file e3ad8915-c9a5-da0e-e053-3705fe0a2b96
|
2
|
|
Novel 1H‑Pyrrolo[2,3‑b]pyridine Derivative Nortopsentin Analogues:
Synthesis and Antitumor Activity in Peritoneal Mesothelioma
Experimental Models, file e3ad8916-9611-da0e-e053-3705fe0a2b96
|
2
|
|
Synthesis of a new class of pyrrolo[3,4-h]quinazolines with antimitotic
activity, file e3ad8916-9e12-da0e-e053-3705fe0a2b96
|
2
|
|
Pyrido[4′,3′:4,5]pyrrolo[2,1-d][1,2,3,5]tetrazines, a new class of Temozolomide heteroanalogues, file e3ad8917-2af7-da0e-e053-3705fe0a2b96
|
2
|
|
[1,2]oxazole[5,4-e]isoindoles as promising drugs for anticancer chemotherapy, file e3ad8918-1566-da0e-e053-3705fe0a2b96
|
2
|
|
[1,2]Oxazolo[5,4-e]isoindoles as promising tubulin polymerization inhibitors, file e3ad891a-5fac-da0e-e053-3705fe0a2b96
|
2
|
|
Pyrrolo[3′,2′:6,7]cyclohepta[1,2-b]pyridines with potent photo-antiproliferative activity, file e3ad891a-958b-da0e-e053-3705fe0a2b96
|
2
|
|
Composti a struttura ossazolica, procedimenti per la loro produzione e loro impiego per la cura di patologie a carattere iperproliferativo, file e3ad891a-975a-da0e-e053-3705fe0a2b96
|
2
|
|
Synthesis and antitumor activity of new 7-azaindole derivative nortopsentin analogues, file e3ad891a-991b-da0e-e053-3705fe0a2b96
|
2
|
|
NUOVI COMPOSTI PIRAZOLO[3,4-H]CHINOLINICI, LORO PREPARAZIONE ED USO MEDICO, file e3ad891a-dfad-da0e-e053-3705fe0a2b96
|
2
|
|
BIOSYNTHESIS OF HEROCYCLES. FROM ISOLATION TO GENE CLUSTER, file e3ad891b-91f1-da0e-e053-3705fe0a2b96
|
2
|
|
Synthesis and photocytotoxic activity of [1,2,3]triazolo[4,5-h][1,6]naphthyridines and [1,3]oxazolo[5,4-h][1,6]naphthyridines, file e3ad891e-c5af-da0e-e053-3705fe0a2b96
|
2
|
|
Imidazo[2,1-b] [1,3,4]thiadiazoles with antiproliferative activity against primary and gemcitabine-resistant pancreatic cancer cells, file e3ad8921-f643-da0e-e053-3705fe0a2b96
|
2
|
|
Eight-Membered Rings With Two Heteroatoms 1,2, file bc556031-ae08-4b67-a786-a1f109ce5f9f
|
1
|
|
PYRROLO[3,2-H]QUINAZOLINE AS PHOTOCHEMOTHERAPEUTIC AGENTS, file e3ad8915-c9a4-da0e-e053-3705fe0a2b96
|
1
|
|
SYNTHESIS AND ANTITUMOR ACTIVITY OF 2,5-BIS(3'-INDOLYL)-FURANS AND 3,5-BIS(3'-INDOLIY)-ISOXAZOLES, NORTOPSENTIN ANALOGUES, file e3ad8915-ca2b-da0e-e053-3705fe0a2b96
|
1
|
|
Nucleophilic substitutions in the isoindole series as a valuable tool to synthesize
derivatives with antitumor activity, file e3ad8915-d505-da0e-e053-3705fe0a2b96
|
1
|
|
7-Azaindole-fused heterocycles with antitumor activity, file e3ad8915-d507-da0e-e053-3705fe0a2b96
|
1
|
|
Pyrrolo[3,2-h]quinazolines as Photochemotherapeutic Agents, file e3ad8915-dd4f-da0e-e053-3705fe0a2b96
|
1
|
|
Condensed azaindole with antitumor activity, file e3ad8915-dd58-da0e-e053-3705fe0a2b96
|
1
|
|
Sintesi chimica di nuovi agenti fotochemioterapici eterociclici, con attività antiproliferativa compresa quella di natura neoplastica, file e3ad8915-f114-da0e-e053-3705fe0a2b96
|
1
|
|
SYNTHESIS OF TETRACYCLIC SYSTEMS WITH POTENT ANTITUMOR ACTIVITY, file e3ad8915-f80d-da0e-e053-3705fe0a2b96
|
1
|
|
Photochemotherapeutic heterocyclic agents having antiproliferative and antineoplastic activity, file e3ad8916-4f5e-da0e-e053-3705fe0a2b96
|
1
|
|
Synthesis and antiproliferative activity of substituted 3[2-(1H-indol-3-yl)-1,3-thiazol-4-yl]-1H-pyrrolo[3,2-b]pyridines, marine alkaloid nortopsentin analogues, file e3ad8916-c890-da0e-e053-3705fe0a2b96
|
1
|
|
11H‑Pyrido[3′,2′:4,5]pyrrolo[3,2‑c]cinnoline and Pyrido[3′,2′:4,5]pyrrolo[1,2‑c][1,2,3]benzotriazine: Two New Ring
Systems with Antitumor Activity, file e3ad8916-ff7b-da0e-e053-3705fe0a2b96
|
1
|
|
Quality characteristics and in vitro digestibility study of barley flour enriched ditalini pasta, file e3ad8918-141b-da0e-e053-3705fe0a2b96
|
1
|
|
Pyrrolocycloheptaoxazole as potent antitumor agents, file e3ad891a-5eac-da0e-e053-3705fe0a2b96
|
1
|
|
Synthesis of the new ring system 6,8-dihydro-5H-pyrrolo[3,4-h]quinazoline, file e3ad891b-2195-da0e-e053-3705fe0a2b96
|
1
|
|
Pyrano[2,3-e]isoindol-2-ones, new angelicin heteroanalogues, file e3ad891b-3db0-da0e-e053-3705fe0a2b96
|
1
|
|
Synthesis of the New Ring System 2-Oxo-[1,4]oxazino[3,2-e]indole, Heteroanalogue of Angelicin, file e3ad891b-4152-da0e-e053-3705fe0a2b96
|
1
|
|
Pyrrolotetrazinones deazaanalogues of temozolomide induce apoptosis in Jurkat cell line: involvement of tubulin polymerization inhibition, file e3ad891b-6ec4-da0e-e053-3705fe0a2b96
|
1
|
|
Synthesis of 5H-pyrido[3,2-b]pyrrolizin-5-one tripentone analogs with antitumor activity, file e3ad891d-9835-da0e-e053-3705fe0a2b96
|
1
|
| Totale |
3.503 |