Among the electrical energy production systems from renewable sources, the photovoltaic one represents today one of the most efficient and technically tested choice. In this paper the authors present a mathematical model that allows the maximization of the generated power of photovoltaic (PV) plants under unequally radiation conditions. In particular, thanks to the model of a PV plant, unequally radiated, developed in Matlab-Simulink environment, in this paper the mismatch problem of PV plants is dealt with. The simulations curried out allow to assert that by putting into action re-configuration techniques of series-parallel connections of PV plants, under unequally radiation, can allow to optimize the electrical energy production from these plants. This result opens scenarios of conceivable modifications to the PV field configurations today chosen during the design stage and unchangeable during the operating stage.