The ability to form a biofilm, bacterial communities able to grow on surfaces and surrounded by an extracellular polymeric substance biofilm agents.Our research group focused on discovering of novel chemical agents of potential therapeutic utility in the treatment of staphylococcal biofilm-associatedinfections by screening novel compounds (synthetic or natural). In a recent study, the antistaphylococcalbiofilm activity of pyrrolomycins C,D, F1, F2a, F2b, F3 a family of halogenated pyrroles which are naturally produced byActinosporangium vitaminophylum and of the synthesized related compounds I, II, III were investigated and compared (Schillaci et al, 2010). We also focused on marine invertebrates as source of new antibiofilm agents and the activity of the 5kDa peptide fraction of the cytosol from coelomocytes of Paracentrotus lividus (sea-urchin) against staphylococcal biofilms was determined

Schillaci, D. (2010). Bacterial biofilms: a challenge in the discovery of new anti-infective agents.. In Atti VIII Congresso Annuale del Dipartimento di Biologia Celulare e dello Sviluppo, Università degli Studi di Palermo (pp.6-7).

Bacterial biofilms: a challenge in the discovery of new anti-infective agents.

SCHILLACI, Domenico
2010-01-01

Abstract

The ability to form a biofilm, bacterial communities able to grow on surfaces and surrounded by an extracellular polymeric substance biofilm agents.Our research group focused on discovering of novel chemical agents of potential therapeutic utility in the treatment of staphylococcal biofilm-associatedinfections by screening novel compounds (synthetic or natural). In a recent study, the antistaphylococcalbiofilm activity of pyrrolomycins C,D, F1, F2a, F2b, F3 a family of halogenated pyrroles which are naturally produced byActinosporangium vitaminophylum and of the synthesized related compounds I, II, III were investigated and compared (Schillaci et al, 2010). We also focused on marine invertebrates as source of new antibiofilm agents and the activity of the 5kDa peptide fraction of the cytosol from coelomocytes of Paracentrotus lividus (sea-urchin) against staphylococcal biofilms was determined
Settore BIO/19 - Microbiologia Generale
20-dic-2010
CONGRESSO ANNUALE DEL DIPARTIMENTO DI BIOLOGIA CELLULARE E DELLO SVILUPPO “A.MONROY” VIALE DELLE SCIENZE ED.16 UNIVERSITÀ DEGLI STUDI 90128 PALERMO
Dipartimento di Biologia Cellulare e dello Sviluppo
20-21 Dicembre 2010
VIII
2
Comunicazione orale
Schillaci, D. (2010). Bacterial biofilms: a challenge in the discovery of new anti-infective agents.. In Atti VIII Congresso Annuale del Dipartimento di Biologia Celulare e dello Sviluppo, Università degli Studi di Palermo (pp.6-7).
Proceedings (atti dei congressi)
Schillaci,D
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/55485
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