Babesia bigemina is an endemic parasite in different parts of the world, including Europe and the Americas. One of the few genes characterized in this species codifies for the apical membrane antigen 1 (AMA-1), a transmembrane antigen recently identified. We characterized the ama-1 gene from three Italian B. bigemina strains. Italian sequences were compared to those of the Australian strain. The results obtained confirmed that this newly described ama-1 gene is highly conserved among Italian and foreign strains, which has implications for vaccine development.
Torina, A., Agnone, A., Sireci, G., Mosqueda, J., Blanda, V., Albanese, I., et al. (2009). Caratterizzazione dell'antigene AMA1 in ceppi di Babesia bigemina isolati in Italia. In XI Congresso Nazionale S.I.Di.L.V. (pp.258-259). Parma.
Caratterizzazione dell'antigene AMA1 in ceppi di Babesia bigemina isolati in Italia
AGNONE, Annalisa;SIRECI, Guido;BLANDA, Valeria;ALBANESE, Ida;LA FARINA, Mario;
2009-01-01
Abstract
Babesia bigemina is an endemic parasite in different parts of the world, including Europe and the Americas. One of the few genes characterized in this species codifies for the apical membrane antigen 1 (AMA-1), a transmembrane antigen recently identified. We characterized the ama-1 gene from three Italian B. bigemina strains. Italian sequences were compared to those of the Australian strain. The results obtained confirmed that this newly described ama-1 gene is highly conserved among Italian and foreign strains, which has implications for vaccine development.
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