The role of the cardiovascular regulatory mechanism in patients with neuromediate syncope (NS) is poorly understood. Aim of this study was to accomplish continuous non-invasive analysis of the baroreflex mechanism in patients during head-up tilt-table test (HTT) using an open loop autoregressive model with exogenous input. The model describes the causal dependence of the RR interval on the systolic arterial pressure (SAP) variability. Thus, RR variability results as the linear composition of SAP-dependent (Pdep) and SAP-independent parts. Further, the model allows the estimation of the baroreflex gain using the modulus of the transfer function (G) from SAP to RR in the low frequency band. Results showed a significant decrease of both Pdep and G immediately before syncope. Thus, a reduced functionality of the baroreflex and of the sympathetic tone seemed to be the mechanism responsible for the NS event.

Widesott, L., Nollo, G., Faes, L., Porta, A., Del Greco, M., Antolini, R. (2001). Spectral decomposition of RR-variability obtained by an open loop parametric model for the diagnosis of neuromediate syncope. In Computers in Cardiology (pp.477-480) [10.1109/CIC.2001.977696].

Spectral decomposition of RR-variability obtained by an open loop parametric model for the diagnosis of neuromediate syncope

Faes, L.;
2001-01-01

Abstract

The role of the cardiovascular regulatory mechanism in patients with neuromediate syncope (NS) is poorly understood. Aim of this study was to accomplish continuous non-invasive analysis of the baroreflex mechanism in patients during head-up tilt-table test (HTT) using an open loop autoregressive model with exogenous input. The model describes the causal dependence of the RR interval on the systolic arterial pressure (SAP) variability. Thus, RR variability results as the linear composition of SAP-dependent (Pdep) and SAP-independent parts. Further, the model allows the estimation of the baroreflex gain using the modulus of the transfer function (G) from SAP to RR in the low frequency band. Results showed a significant decrease of both Pdep and G immediately before syncope. Thus, a reduced functionality of the baroreflex and of the sympathetic tone seemed to be the mechanism responsible for the NS event.
2001
Annual Meeting on Computers in Cardiology
Rotterdam
23-26 September, 2001
28
2001
4
Widesott, L., Nollo, G., Faes, L., Porta, A., Del Greco, M., Antolini, R. (2001). Spectral decomposition of RR-variability obtained by an open loop parametric model for the diagnosis of neuromediate syncope. In Computers in Cardiology (pp.477-480) [10.1109/CIC.2001.977696].
Proceedings (atti dei congressi)
Widesott, L.; Nollo, G.; Faes, L.; Porta, A.; Del Greco, M.; Antolini, R.
File in questo prodotto:
File Dimensione Formato  
A05-CiC2001-widesott.pdf

Solo gestori archvio

Dimensione 285.34 kB
Formato Adobe PDF
285.34 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/278836
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 1
  • ???jsp.display-item.citation.isi??? 1
social impact