Early Endometrial Cancer. Case-control study to evaluate the efficacy and safety of the new Robotic Single-site System

Objective: To compare surgical and cosmetic outcomes of robotic single-site (RSS) versus robotic multiport (RMP) approaches in early stage endometrial cancer. Methods: This is a perspective case-control study, comparing perioperative and early post-operative outcomes in RSS (cases) and RMP (controls) patients with early stage endometrial cancer. Clinical data including patient's demographics and peri-operative measures were recorded. Complications, hospital stay and post-operative pain were also considered. Cosmetic result was evaluated with Patient and Observer Scar Assessment Scale (POSAS). Results: A total of 15 women who underwent RSS were matched with 13 controls treated by RMP. No significant differences were found in terms of age, histologic type, stage, and grading. The mean operative time was similar (p=0.431) and also blood loss (p=0.611). No intra-operative complications occurred in both groups. The POSAS scores confirmed excellent cosmetic outcome of the RSS approach. Conclusion: Our study suggests the safety and feasibility of RSS for staging early endometrial cancer without major differences from the RMP in terms of surgical outcomes. The POSAS revealed a significant higher evaluated cosmetic outcome in RSS patients.