Giuffrè G.:
Indocyanine green angiography in congenital hypertrophy of the retinal pigment
epithelium.
Eur J Ophthalmol. 2005;15:162-4.


PURPOSE: To report a case of congenital hypertrophy of the retinal pigment
epithelium followed up for 7 years showing features not previously reported.
METHODS: A complete fundus examination including fluorescein angiography was
performed at first examination and at follow-up.
RESULTS: The area of congenital hypertrophy of the retinal pigment epithelium
presented morphologic changes, showing enlargement of the lesion on one side
associated with partial regression on another side. In addition, the indocyanine 
green angiography findings revealed that this test was more useful than
fluorescein angiography to delineate the real boundaries of the lesion and
disclosed hypofluorescent areas inside the main lesion that were not appreciated 
at ophthalmoscopy or fluorescein angiography.
CONCLUSIONS: Indocyanine green angiography is an useful test to understand the
findings and evolution of congenital hypertrophy of the retinal pigment
epithelium.