Schiff base complexes derived from N,N!-bridged tetradentate ligands involving N2O2 donor atoms present very favourable features to act as G4 binders. Thus, a series of square-planar and square pyramidal metal complexes, ML2+ (M = Ni, Cu, and Zn), have been synthesized and characterized.
Terenzi, A., Bonsignore, R., Gentile, C., Martorana, A., Barone, G., Lauria, A., et al. (2013). SELECTIVE G-QUADRUPLEX STABILIZERS: SALPHEN-LIKE COMPLEXES WITH ANTIPROLIFERATIVE ACTIVITY. In XXII National Meeting on Medicinal Chemistry Italian Chemical Society Division of Medicinal Chemistry September 10-13, Roma - Italy Abstract Book.
SELECTIVE G-QUADRUPLEX STABILIZERS: SALPHEN-LIKE COMPLEXES WITH ANTIPROLIFERATIVE ACTIVITY
TERENZI, Alessio;Bonsignore, Riccardo;GENTILE, Carla;MARTORANA, Annamaria;BARONE, Giampaolo;LAURIA, Antonino;ALMERICO, Anna Maria
2013-01-01
Abstract
Schiff base complexes derived from N,N!-bridged tetradentate ligands involving N2O2 donor atoms present very favourable features to act as G4 binders. Thus, a series of square-planar and square pyramidal metal complexes, ML2+ (M = Ni, Cu, and Zn), have been synthesized and characterized.
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