AIM: The aim of the study was to investigate the utility of NT-proBNP measurement for the stratification of presurgical cardiac risk. METHODS: Cardiac risk before elective non-cardiac surgery was evaluated in 82 consecutive patients. From each patient a venous blood sample was drawn to determinate NT-proBNP levels. Patients were followed up over three months in order to detect the occurrence of cardiac adverse events. RESULTS: NT-proBNP was positively correlated (P<0.0001) with age, days of hospitalization (P=0.001) and ASA class (P=0.001). High surgical risk (P<0.0001), diabetes (P=0.004), dyslipidemia (P=0.006) and elevated levels of NT-proBNP (P<0.0001) were significantly correlated with events. Using a logistic regression analysis we found an independent association between pre-operative elevated NT-proBNP and postoperative cardiac events (OR 1.2, 95% CI 1.0-1.4, P=0.01). CONCLUSION: Measuring NT-proBNP before non cardiac surgery in clinical practice could be useful to better stratify patients' risk.

Novo, G., Corrado, E., Tortorici, E., Novo, A., Agrusa, A., Saladino, V., et al. (2011). Cardiac risk stratification in elective non-cardiac surgery: role of NT-proBNP. INTERNATIONAL ANGIOLOGY, 30(3), 242-246.

Cardiac risk stratification in elective non-cardiac surgery: role of NT-proBNP

NOVO, Giuseppina;CORRADO, Egle;TORTORICI, Enza;AGRUSA, Antonino;SALADINO, Vita Anna;VISCONTI, Claudia Luisa;MASSENTI, Maria Fatima;D'ARIENZO, Michele;VITALE, Francesco;GULOTTA, Gaspare;NOVO, Salvatore
2011-01-01

Abstract

AIM: The aim of the study was to investigate the utility of NT-proBNP measurement for the stratification of presurgical cardiac risk. METHODS: Cardiac risk before elective non-cardiac surgery was evaluated in 82 consecutive patients. From each patient a venous blood sample was drawn to determinate NT-proBNP levels. Patients were followed up over three months in order to detect the occurrence of cardiac adverse events. RESULTS: NT-proBNP was positively correlated (P<0.0001) with age, days of hospitalization (P=0.001) and ASA class (P=0.001). High surgical risk (P<0.0001), diabetes (P=0.004), dyslipidemia (P=0.006) and elevated levels of NT-proBNP (P<0.0001) were significantly correlated with events. Using a logistic regression analysis we found an independent association between pre-operative elevated NT-proBNP and postoperative cardiac events (OR 1.2, 95% CI 1.0-1.4, P=0.01). CONCLUSION: Measuring NT-proBNP before non cardiac surgery in clinical practice could be useful to better stratify patients' risk.
2011
Novo, G., Corrado, E., Tortorici, E., Novo, A., Agrusa, A., Saladino, V., et al. (2011). Cardiac risk stratification in elective non-cardiac surgery: role of NT-proBNP. INTERNATIONAL ANGIOLOGY, 30(3), 242-246.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/79260
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