Novel lineages of human astrovirus (HAstV) types 2, 2c, and 2d have been identified. Upon sequencing of the 3= end of the genome, the type 2c and 2d HAstVs were found to be open reading frame 1b (ORF1b)-ORF2 recombinant, with ORF1b being derived from type 3 and type 1 HAstVs, respectively. An ORF2 interlineage recombinant strain, 2c/2b, was also identified.
De Grazia, S., Medici, M.C., Pinto, P., Moschidou, P., Tummolo, F., Calderaro, A., et al. (2012). Genetic heterogeneity and recombination in human type 2 astroviruses. JOURNAL OF CLINICAL MICROBIOLOGY, 50(11), 3760-3764 [10.1128/JCM.02102-12.].
Genetic heterogeneity and recombination in human type 2 astroviruses
DE GRAZIA, Simona;GIAMMANCO, Giovanni;
2012-01-01
Abstract
Novel lineages of human astrovirus (HAstV) types 2, 2c, and 2d have been identified. Upon sequencing of the 3= end of the genome, the type 2c and 2d HAstVs were found to be open reading frame 1b (ORF1b)-ORF2 recombinant, with ORF1b being derived from type 3 and type 1 HAstVs, respectively. An ORF2 interlineage recombinant strain, 2c/2b, was also identified.
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