We investigated the association between age at onset of Parkinson's disease (PD) and fertile life characteristics in 145 women. Linear regression analyses showed a significant correlation between age at PD onset and age at menopause (P = 0.003), between age at PD onset and fertile life duration (P = 0.008), and a nonsignificant correlation between PD onset and cumulative duration of pregnancies (P = 0.23). These results support the possible role of estrogens in PD.
RAGONESE P, D'AMELIO M, CALLARI G, SALEMI G, MORGANTE L, SAVETTIERI G (2006). Age at menopause predicts age at onset of Parkinson's disease. MOVEMENT DISORDERS, 21(12), 2211-2214 [10.1002/mds.21127].
Age at menopause predicts age at onset of Parkinson's disease.
RAGONESE, Paolo;D'AMELIO, Marco;CALLARI, Graziella;SALEMI, Giuseppe;SAVETTIERI, Giovanni
2006-01-01
Abstract
We investigated the association between age at onset of Parkinson's disease (PD) and fertile life characteristics in 145 women. Linear regression analyses showed a significant correlation between age at PD onset and age at menopause (P = 0.003), between age at PD onset and fertile life duration (P = 0.008), and a nonsignificant correlation between PD onset and cumulative duration of pregnancies (P = 0.23). These results support the possible role of estrogens in PD.
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