N-(1-Phenyl-4-carbetoxypyrazol-5-yl)-, N-(indazol-3-yl)- and N-(indazol-5-yl)-2-iodobenzamides 6, with a Benodanil-like structure, were synthesized by refluxing in acetic acid the corresponding benzotriazinones 5 with potassium iodide for 1 h in order to study the role on the antifungal activity of the N-substitution with an aromatic heterocyclic system on benzamide moiety. Among the tested iododerivatives, compounds 6d,f,g,h possess interesting activities toward some phytopathogenic fungal strains.

Raffa, D., Daidone, G., Plescia, F., Schillaci, D., Maggio, B., Torta, L. (2002). Synthesis and antifungal activity of new N-(1-phenil-4-carbetoxypyrazol-5-yl)-N-(indazol-3-yl)- and N-(indazol-5-yl)-2-iodobenzamides. IL FARMACO, 57, 183-187 [10.1016/S0014-827X(01)01190-9].

Synthesis and antifungal activity of new N-(1-phenil-4-carbetoxypyrazol-5-yl)-N-(indazol-3-yl)- and N-(indazol-5-yl)-2-iodobenzamides

RAFFA, Demetrio;DAIDONE, Giuseppe;MAGGIO, Benedetta;TORTA, Livio
2002-01-01

Abstract

N-(1-Phenyl-4-carbetoxypyrazol-5-yl)-, N-(indazol-3-yl)- and N-(indazol-5-yl)-2-iodobenzamides 6, with a Benodanil-like structure, were synthesized by refluxing in acetic acid the corresponding benzotriazinones 5 with potassium iodide for 1 h in order to study the role on the antifungal activity of the N-substitution with an aromatic heterocyclic system on benzamide moiety. Among the tested iododerivatives, compounds 6d,f,g,h possess interesting activities toward some phytopathogenic fungal strains.
2002
Settore CHIM/08 - Chimica Farmaceutica
Raffa, D., Daidone, G., Plescia, F., Schillaci, D., Maggio, B., Torta, L. (2002). Synthesis and antifungal activity of new N-(1-phenil-4-carbetoxypyrazol-5-yl)-N-(indazol-3-yl)- and N-(indazol-5-yl)-2-iodobenzamides. IL FARMACO, 57, 183-187 [10.1016/S0014-827X(01)01190-9].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/61021
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