The type 2 diabetes is commonly considered a complex genetic disease, resulting from interactions between multiple genes and environmental factors without any single factor having strong independent effects. We studied the influence of family history to type 2 diabetes on physical phenotype of 47 health adolescents. In both sexes groups with positive family history (FH+) had the highest values of stature and body weight (p<0.05 for males, not significant for females), waist circumference (p<0.05 for males, not significant for females), and wrist circumference (p=0.05 for males, not significant for females). Considering performance, FH+ males showed a significant higher performance in power exercises than FH- males; no significant differences were found between FH+ and FH- female groups. Family history to type 2 diabetes can induce in both sexes precocious phenotype and performances linked-related variations; more studies are necessary to confirm these data and to verify preventive interventions promoting significant life-style changes.
Bianco, A., Pomara, F., Basile, D., Petrucci, M., Battaglia, G., Paoli, A., et al. (2010). INFLUENCE OF FAMILY HISTORY OF TYPE 2 DIABETES ON PHENOTYPE AND PERFORMANCE IN YOUNG PEOPLE OF BOTH SEX. RIVISTA DELLA FACOLTÀ DI SCIENZE MOTORIE DELL'UNIVERSITÀ DEGLI STUDI DI PALERMO, III(1), 127-136.
INFLUENCE OF FAMILY HISTORY OF TYPE 2 DIABETES ON PHENOTYPE AND PERFORMANCE IN YOUNG PEOPLE OF BOTH SEX.
BIANCO, Antonino;PETRUCCI, Marco;BATTAGLIA, Giuseppe;BELLAFIORE, Marianna;PALMA, Antonio
2010-01-01
Abstract
The type 2 diabetes is commonly considered a complex genetic disease, resulting from interactions between multiple genes and environmental factors without any single factor having strong independent effects. We studied the influence of family history to type 2 diabetes on physical phenotype of 47 health adolescents. In both sexes groups with positive family history (FH+) had the highest values of stature and body weight (p<0.05 for males, not significant for females), waist circumference (p<0.05 for males, not significant for females), and wrist circumference (p=0.05 for males, not significant for females). Considering performance, FH+ males showed a significant higher performance in power exercises than FH- males; no significant differences were found between FH+ and FH- female groups. Family history to type 2 diabetes can induce in both sexes precocious phenotype and performances linked-related variations; more studies are necessary to confirm these data and to verify preventive interventions promoting significant life-style changes.
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