Many biological systems can be described as networks where diFFerent elements interact, in order to perform biological processes. We introduce a network associated with the Gene Ontology. Specifically, we construct a correlation-based network where the vertices are the terms of the Gene Ontology and the link between each two terms is weighted on the basis of the number of genes that they have in common. We analyze a filtered network obtained from the correlation-based network and we characterize its evolution over different releases of the Gene Ontology.

Coronnello, C., Tumminello, M., Micciche', S., Mantegna, R.N. (2009). Networks in biological systems: An investigation of the Gene Ontology as an evolving network. IL NUOVO CIMENTO C, 32(2), 157-160 [10.1393/ncc/i2009-10386-7].

Networks in biological systems: An investigation of the Gene Ontology as an evolving network

CORONNELLO, Claudia;TUMMINELLO, Michele;MICCICHE', Salvatore;MANTEGNA, Rosario Nunzio
2009-01-01

Abstract

Many biological systems can be described as networks where diFFerent elements interact, in order to perform biological processes. We introduce a network associated with the Gene Ontology. Specifically, we construct a correlation-based network where the vertices are the terms of the Gene Ontology and the link between each two terms is weighted on the basis of the number of genes that they have in common. We analyze a filtered network obtained from the correlation-based network and we characterize its evolution over different releases of the Gene Ontology.
2009
Settore FIS/07 - Fisica Applicata(Beni Culturali, Ambientali, Biol.e Medicin)
Coronnello, C., Tumminello, M., Micciche', S., Mantegna, R.N. (2009). Networks in biological systems: An investigation of the Gene Ontology as an evolving network. IL NUOVO CIMENTO C, 32(2), 157-160 [10.1393/ncc/i2009-10386-7].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/44551
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