The porosity and pore size distribution of three-dimensional scaffolds have direct implications on their biomedical applications (tissue engineering, drug delivery, and wound dressing). Accordingly, in this paper, a fast, facile, and conservative method relying on low-field nuclear magnetic resonance (LF-NMR) for the evaluation of mean pore size and pore size distribution of polymeric scaffolds is reported. The applicability of the technique is demonstrated on poly-L-lactic acid scaffolds fabricated using the thermal induced phase separation. Results obtained through LF-NMR are successfully compared to scanning electron microscope and X-ray microcomputed tomography micrographs

Fiorentino, S., Carfì Pavia, F., La Carrubba, V., Brucato, V., Abrami, M., Farra, R., et al. (2017). Characterization of PLLA scaffolds for biomedical applications. INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS, 66(9), 469-477 [10.1080/00914037.2016.1252344].

Characterization of PLLA scaffolds for biomedical applications

La Carrubba, Vincenzo;CARFI' PAVIA, Francesco;BRUCATO, Valerio Maria Bartolo
2017-01-01

Abstract

The porosity and pore size distribution of three-dimensional scaffolds have direct implications on their biomedical applications (tissue engineering, drug delivery, and wound dressing). Accordingly, in this paper, a fast, facile, and conservative method relying on low-field nuclear magnetic resonance (LF-NMR) for the evaluation of mean pore size and pore size distribution of polymeric scaffolds is reported. The applicability of the technique is demonstrated on poly-L-lactic acid scaffolds fabricated using the thermal induced phase separation. Results obtained through LF-NMR are successfully compared to scanning electron microscope and X-ray microcomputed tomography micrographs
2017
Settore ING-IND/22 - Scienza E Tecnologia Dei Materiali
Settore ING-IND/24 - Principi Di Ingegneria Chimica
Fiorentino, S., Carfì Pavia, F., La Carrubba, V., Brucato, V., Abrami, M., Farra, R., et al. (2017). Characterization of PLLA scaffolds for biomedical applications. INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS, 66(9), 469-477 [10.1080/00914037.2016.1252344].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/260295
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