Healthy controls are subjects without the disease being studied but may have other conditions indirectly affecting outcome. In the present epidemics of obesity a few subjects with undiagnosed nonalcoholic fatty liver disease enter clinical studies as controls, producing biased results. Stricter selection criteria should be considered to prevent this risk.

Marchesini, G., Marchignoli, F., Petta, S. (2017). Evidence-Based Medicine and the Problem of Healthy Volunteers. ANNALS OF HEPATOLOGY, 16(6), 832-834 [10.5604/01.3001.0010.5272].

Evidence-Based Medicine and the Problem of Healthy Volunteers

Petta, Salvatore
Membro del Collaboration Group
2017-01-01

Abstract

Healthy controls are subjects without the disease being studied but may have other conditions indirectly affecting outcome. In the present epidemics of obesity a few subjects with undiagnosed nonalcoholic fatty liver disease enter clinical studies as controls, producing biased results. Stricter selection criteria should be considered to prevent this risk.
2017
Marchesini, G., Marchignoli, F., Petta, S. (2017). Evidence-Based Medicine and the Problem of Healthy Volunteers. ANNALS OF HEPATOLOGY, 16(6), 832-834 [10.5604/01.3001.0010.5272].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/247545
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