BACKGROUND: The aim of this study was to evaluate the use of a new collagen matrix (Mucograft®; Geistlich Pharma AG, Wolhusen, Switzerland) to improve the wound healing after bioptic excision. Often a bioptic excision of mucosal lesions is needed to perform an histological examination of the lesion. In some case after the surgery tissues can heal for secondary intention resulting in the presence of cicatrizations. It has been demonstrated that thanks to their compact struc- ture, collagen matrices work as scaffold and they accelerate the migration of epithelial cells in the wound tissues. In fact reconstruction after rescission of mucosal biopsy requires the levy of a graft from the patients or healing by second- ary intention that often improve morbility. Nowadays, a new col- lagen matrix is available to avoid surgical grafts and improve the postoperatory confort. METHODS: Mucograft® is a pure collagen type I and III matrix of porcine origin without further cross-linking. Up today, clinicians have been mainly focused on the use of Mucograft® in periodontal procedures, such as: treatment of recessions on teeth and implants and increment in the amount of keratinized gingiva. The effectiveness of this matrix for the use in the oral wound healing has already been validated by in vitro and in vivo studies. In fact, this porcine membrane stimulate an increased production of proinflammatory mediators in the mononuclear cells and a decreasement in cellular proliferation. In addition, a good proliferative activity of fibroblasts has also been seen, in both the layers of the matrix. In this work we report a case of a fistula between the nose and the oral cavity closed after the bioptical excision of the lesion and the positioning of the collagen matrix. RESULTS: Histological examination stained with hematoxy- lin and eosin revealed that the lesion derived from a previous nasopalatine duct cyst. After 2 months from surgery a correct healing of the tissues was visible and a complete closure of the communication way was present. CONCLUSIONS: We think this material should be well investigated for its use in oral mucosal surgery, due to its biological features that take it capable to improve both func- tional and aesthetic parameters.
G., L., G., I., M. E., L., Giancola, F., P., T., G., T., et al. (2016). Close of a fistula between the nose and the oral cavity using a new collagen matrix. In MINERVA STOMATOLOGICA (pp.28-28).
|Autori:||G., L.; G., I.; M. E., L.; Giancola, F.; P., T.; G., T.; L., L.|
|Titolo:||Close of a fistula between the nose and the oral cavity using a new collagen matrix|
|Data di creazione:||2015-04-14|
|Nome del convegno:||XXIII Congresso Nazionale del Collegio dei Docenti Universitari di discipline Odontostomatologiche|
|Data di pubblicazione:||2016|
|Numero di pagine:||1|
|Citazione:||G., L., G., I., M. E., L., Giancola, F., P., T., G., T., et al. (2016). Close of a fistula between the nose and the oral cavity using a new collagen matrix. In MINERVA STOMATOLOGICA (pp.28-28).|
|Tipologia:||0 - Proceedings (TIPOLOGIA NON ATTIVA)|
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