Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a severe adverse event related to bisphosphonates (BPs) therapy; tooth extraction has been described as the main trigger. Autologous platelet concentrates, such Leukocyte-Platelet Rich Fibrin (L-PRF, Intraspin !) are designed to release platelet growth factors, improving the tissue healing in oral surgery. The aim of this study was to evaluate the efficacy and safety of our dental extraction protocol applied in BPs patients.
Mauceri, R., Giancola, F., Panzarella, V., Tozzo, P., Campisi, G., Di Fede, O. (2016). L-PRF application in extraction sockets of bisphosphonate-treated patients: preliminary results. ORAL DISEASES, 50-50.
L-PRF application in extraction sockets of bisphosphonate-treated patients: preliminary results
Mauceri, Rodolfo;Giancola, Francesco;PANZARELLA, Vera;CAMPISI, Giuseppina;DI FEDE, Olga
2016-01-01
Abstract
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a severe adverse event related to bisphosphonates (BPs) therapy; tooth extraction has been described as the main trigger. Autologous platelet concentrates, such Leukocyte-Platelet Rich Fibrin (L-PRF, Intraspin !) are designed to release platelet growth factors, improving the tissue healing in oral surgery. The aim of this study was to evaluate the efficacy and safety of our dental extraction protocol applied in BPs patients.
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