Impact of virus eradication in patients with compensated hepatitis C virus-related cirrhosis: competing risks and multistate model

No published study to date has provided a careful analysis of the effects of a sustained viral response(SVR) on the outcomes of patients with compensated hepatitis C virus(HCV)-related cirrhosis in relation to the degree of portal hypertension. Therefore, we estimated the impact of achieving SVR on disease progression, hepatocellular carcinoma(HCC) development and mortality in a large cohort of HCV patients with cirrhosis with or without oesophageal varices(OVs) at the start of antiviral therapy.