OBJECTIVE: To investigate the difference of long-term amenorrhea rate in patients with menorrhagia treated by endometrial laser intrauterine thermal therapy (ELITT), a new nonhysteroscopic endometrial ablation procedure, versus transcervical hysteroscopic endometrial resection (TCRE). DESIGN: Randomized clinical study. Healthy volunteers in an academic research environment. SETTING: Academic teaching hospital. PATIENT(S): Premenopausal women with abnormal uterine bleeding. INTERVENTION(S): Fifty-eight patients were treated with the ELITT procedure and 58 patients with TCRE; both groups were treated with GnRH agonists before the procedure. MAIN OUTCOME MEASURE(S): Bleeding status and patient satisfaction after treatment were evaluated as well as the intraoperative complication rate. RESULT(S): At 12 months, the amenorrhea rate was 56% in the ELITT group and 23% in the TCRE group. At 36 months, the figures were 61% for ELITT and 24% for TCRE. No significant complications were recorded for either procedure. CONCLUSION(S): Results of this randomized study demonstrate that both procedures are equally effective in the treatment of menorrhagia. However, the ELITT procedure has proven to be superior in inducing amenorrhea.
|Data di pubblicazione:||2004|
|Titolo:||A RANDOMIZED COMPARISON OF ENDOMETRIAL LASER INTRAUTERINE THERMOTHERAPY AND HYSTEROSCOPY ENDOMETRIAL RESECTION|
|Autori:||PERINO A; CASTELLI A; CUCINELLA G; BIONDO A; PANE A; VENEZIA R|
|Tipologia:||Articolo su rivista|
|Citazione:||PERINO A, CASTELLI A, CUCINELLA G, BIONDO A, PANE A, & VENEZIA R (2004). A RANDOMIZED COMPARISON OF ENDOMETRIAL LASER INTRAUTERINE THERMOTHERAPY AND HYSTEROSCOPY ENDOMETRIAL RESECTION. FERTILITY AND STERILITY, 82, 731-734.|
|Digital Object Identifier (DOI):||10.1016/j.fertnstert.2004.01.045|
|Appare nelle tipologie:||01 - Articolo su rivista|