We present here a compact overview of the data, models and methods proposed for the analysis of biological networks based on the search for significant repetitions. In particular, we concentrate on three problems widely studied in the literature: 'network alignment', 'network querying' and 'network motif extraction'. We provide (i) details of the experimental techniques used to obtain the main types of interaction data, (ii) descriptions of the models and approaches introduced to solve such problems and (iii) pointers to both the available databases and software tools. The intent is to lay out a useful roadmap for identifying suitable strategies to analyse cellular data, possibly based on the joint use of different interaction data types or analysis techniques.

Panni, S., Rombo, S. (2015). Searching for repetitions in biological networks: methods, resources and tools. BRIEFINGS IN BIOINFORMATICS, 16(1), 118-136 [10.1093/bib/bbt084].

Searching for repetitions in biological networks: methods, resources and tools

ROMBO, Simona Ester
2015-01-01

Abstract

We present here a compact overview of the data, models and methods proposed for the analysis of biological networks based on the search for significant repetitions. In particular, we concentrate on three problems widely studied in the literature: 'network alignment', 'network querying' and 'network motif extraction'. We provide (i) details of the experimental techniques used to obtain the main types of interaction data, (ii) descriptions of the models and approaches introduced to solve such problems and (iii) pointers to both the available databases and software tools. The intent is to lay out a useful roadmap for identifying suitable strategies to analyse cellular data, possibly based on the joint use of different interaction data types or analysis techniques.
2015
Settore INF/01 - Informatica
Panni, S., Rombo, S. (2015). Searching for repetitions in biological networks: methods, resources and tools. BRIEFINGS IN BIOINFORMATICS, 16(1), 118-136 [10.1093/bib/bbt084].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10447/137912
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