Several 1,3-thiazolidin-4-ones bearing a 2,6-dihalophenyl group at C-2 and a variously substituted phenyl ring at N-3 have been synthesized and tested as anti-HIV agents. The results of the in vitro tests showed that some of them proved to be effective inhibitors of HIV-1 replication.
Rao, A., Carbone, A., Chimirri, A., De Clercq, E., Monforte, A., Monforte, P., et al. (2002). Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-ones. IL FARMACO, 58(58), 115-120.
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-ones.
CARBONE, Anna;
2002-01-01
Abstract
Several 1,3-thiazolidin-4-ones bearing a 2,6-dihalophenyl group at C-2 and a variously substituted phenyl ring at N-3 have been synthesized and tested as anti-HIV agents. The results of the in vitro tests showed that some of them proved to be effective inhibitors of HIV-1 replication.
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